Zhao Published Research Reveals How Mutation Contributes to Fragile X

Fragile X Normal and Mutant

“This is the first direct evidence that mitochondria dysfunction contributes to fragile X and autism. I hope it will open up new therapeutic developments.”

– Xinyu Zhao

UW-Madison research published in Nature Neuroscience, Volume 22, pages 386–400 (2019) reveals how one mutation causes fragile X, the most common inherited intellectual disability.

“Fragile X syndrome has been studied as a model of intellectual disability because in theory it’s comparatively simple,” says senior author Dr. Xinyu Zhao, a professor of neuroscience in the Waisman Center at the University of Wisconsin–Madison.

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Click here for full paper.